Captain Greig Laidlaw (shoulder) has been ruled out and is replaced by Gregor Hunter as one of five changes from the side which lost 45-0 to Saracens last weekend.
Scotland tighthead Geoff Cross has been named to start, with Fiji captain Netani Talei brought in at number eight.
Talei's selection sees Stuart McInally accommodated at openside flanker at the expense of Ross Rennie, in a big back row, which also features David Denton.
Greig Tonks and Ben Atiga have recovered from hand and hip injuries respectively to be named at full-back and centre.
Tonks has started every available match since joining from Northampton in the summer.
Munster lost their opening match 22-17 to Racing Metro and Bradley knows a win in Limerick is essential if Edinburgh are to emulate their run to last year's semi-finals.
"There's no doubt that this is a massive game for us, but it's also a big chance for us to get our European Cup campaign moving and challenge the teams in this group," Bradley said.
"Thomond Park is a fortress, steeped in the Heineken Cup history. The fans and the players will be fired up for this, so we'll need to front up to the physical aspects of the game from the outset.
"If we match them physically, and are patient and accurate in possession, then we have a chance to impose our game plan and not be dictated to by the Munster players and a Thomond Park crowd that will be desperate for a home win."
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The entire All Blacks apparel line has been updated for 2013/14. Check out the New Zealand All Blacks polo.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Gilbert Blitz 8S rugby cleat is a great cleat at a great price of $69.99. Get a new pair of cleats today.
A cool looking all black rugby cleat with the high performance adidas is known for. Get in the Gear!
Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
$29.99
The All Blacks Performance t-shirt is black with hints of blue from the training jersey. Very Cool.
The New Zealand All Blacks training jersey for 2013/14. Get in the Gear!
The USA Rugby Pro Alternate rugby jersey is perfect for any fan of the Eagles. Get yours to wear during the summer Test matches.
The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.