Last Saturday saw Gloucester win on the road for the first time this season and that will have given the side a real boost ahead of the trip to France.
As a result, Redpath only brings two new faces into the line-up. With Eliota Fuimaono-Sapolu unavailable due to suspension, Henry Trinder will partner Mike Tindall in the Gloucester midfield with Tindall moving to inside centre.
In the pack, Buxton is back on the blindside and will captain the side with Alasdair Strokosch shifting across to number eight.
The one change to the replacements sees Jonny May return after injury and Redpath, while admitting his side will go in as underdogs, has told his players to enjoy the occasion.
"They're probably the best side in European history. So, you have to go there and you have to and make sure your mindset is right," he said.
"But the expectation on us is very low but, internally, we know that we have to be dogged and confident in ourselves and have a real go at them.
"There's no point going there and sitting back and waiting for them to have a go at you. We have to keep possession in the right areas, avoid loose kicks and soft turnovers and maintain the intensity we've shown in the past two weeks.
"But, it's an exciting place to go to, a great place to play rugby and our players should be thriving on it and not fearing it."
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