Warriors make a further four changes as they look to maintain their slim hopes of qualifying for the semi-finals.
John Andress and Alex Lutui return to bolster the front-row.
Chris Pennell and Andy Goode come into the backs to complete the side.
Saracens makes seven changes to last week's line-up. Alex Goode and Duncan Taylor are away on international duty and are replaced by Jack Wilson and Sam Stanley.
Alastair Hargreaves and Alex Rae both come in to form a new second-row partnership.
Ernst Joubert, Justin Melck and Petrus de Plessis are all added to bolster the pack.
Worcester head coach Richard Hill said: "Last weekend our set piece was good and our attack play was promising as we scored three tries away from home in the second half. Our discipline, by only conceding ten penalties, was also encouraging.
"Our defence was not as strong as it should be, but that has been addressed this week and there is no doubt about that. Phil Larder has been in and the players are under no illusions that that performance was totally unacceptable. It will be put right."
Worcester: 15 Chris Pennell, 14 Josh Drauniniu, 13 Jon Clarke, 12 Josh Matavesi, 11 David Lemi, 10 Andy Goode, 9 Jonny Arr, 8 Blair Cowan, 7 Jake Abbott, 6 Richard de Carpentier, 5 Craig Gillies, 4 James Pervical, 3 John Andress, 2 Aleki Lutui, 1 Ceri Jones.
Replacements: 16 Ed Shervington, 17 Rob O'Donnell, 18 James Currie, 19 Matt Kvesic, 20 Neil Best, 21 Paul Hodgson, 22 Danny Gray, 23 Andy Short.
Saracens: 15 Joe Maddock, 14 Jack Wilson, 13 Sam Stanley, 12 Adam Powell, 11 James Short, 10 Nils Mordt (c), 9 Ben Spencer, 8 Ernst Joubert, 7 Nick Fenton-Wells, 6 Justin Melck, 5 Alex Rae, 4 Alistair Hargreaves, 3 Petrus du Plessis, 2 Jamie George, 1 Nick Auterac.
Replacements: 16 John Smit, 17 Richard Barrington, 18 Matt Stevens, 19 Maro Itoje, 20 Jackson Wray, 21 Luke Baldwin, 22 Chris Wyles, 23 Ben Ransom.
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The entire All Blacks apparel line has been updated for 2013/14. Check out the New Zealand All Blacks polo.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Gilbert Blitz 8S rugby cleat is a great cleat at a great price of $69.99. Get a new pair of cleats today.
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Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
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The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.