In a positional switch, Elliot Daly is back at outside centre having featured on the wing and at full-back in the two most recent games.
Wasps go into the game in good form, with five wins in their last seven games in the Aviva Premiership and a 100 per cent record at Adams Park this season.
And they have already been beaten by Bath this season - 30-23 in September at The Rec.
Nick Abendanon, Stuart Hooper and Dominic Day all return to the Bath starting line-up this weekend.
Abendanon comes back in at full-back, replacing Ollie Devoto. Horacio Agulla and Tom Biggs continue on the wings, with Matt Banahan and Kyle Eastmond combining in the centres once more. Stephen Donald and Michael Claassens also continue their half-back partnership.
Hooper and Day form a new second-row partnership, with Dave Attwood shifting to the bench.
Paul James, Lee Mears and David Wilson are unchanged in the front row, as are Francois Louw, Guy Mercer and Ben Skirving at the back of the pack.
Wasps: 15 Hugo Southwell (c), 14 Christian Wade, 13 Elliot Daly, 12 Chris Bell, 11 Tom Varndell, 10 Stephen Jones, 9 Joe Simpson, 8 Billy Vunipola, 7 James Haskell, 6 Ashley Johnson, 5 James Cannon, 4 Joe Launchbury, 3 Phil Swainston, 2 T Rhys Thomas, 1 Zak Taulafo.
Replacements: 16 Tom Lindsay, 17 Tim Payne, 18 Will Taylor, 19 Marco Wentzel, 20 Sam Jones, 21 Charlie Davies, 22 Nick Robinson, 23 Andrea Masi.
Bath: 15 Nick Abendanon, 14 Horacio Agulla, 13 Kyle Eastmond, 12 Matt Banahan, 11 Tom Biggs, 10 Stephen Donald, 9 Michael Claassens, 8 Ben Skirving, 7 Guy Mercer, 6 Francois Louw, 5 Dominic Day, 4 Stuart Hooper (capt), 3 David Wilson, 2 Lee Mears, 1 Paul James.
Replacements: 16 Tom Dunn, 17 Charlie Beech, 18 Anthony Perenise, 19 Dave Attwood, 20 Will Skuse, 21 Mark McMillan, 22 Tom Heathcote, 23 Dan Hipkiss.
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The entire All Blacks apparel line has been updated for 2013/14. Check out the New Zealand All Blacks polo.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Gilbert Blitz 8S rugby cleat is a great cleat at a great price of $69.99. Get a new pair of cleats today.
A cool looking all black rugby cleat with the high performance adidas is known for. Get in the Gear!
Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
The All Blacks Performance t-shirt is black with hints of blue from the training jersey. Very Cool.
The New Zealand All Blacks training jersey for 2013/14. Get in the Gear!
The USA Rugby Pro Alternate rugby jersey is perfect for any fan of the Eagles. Get yours to wear during the summer Test matches.
The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.