The English side, who are unbeaten after victories over Racing Metro and Edinburgh, will have ambitions of claiming the spoils at one of the fortresses of European rugby but have lost all three of their previous meetings with the Irish.
Charlie Hodgson is the tournament's leading scorer after the first two rounds with 40 points.
Saracens have a 100% success rate on their own throw at the line-out this season, retaining ball on all 23 throws so far as well as stealing a competition high six opposition throws. Munster are also joint-top of the line-outs stolen chart, averaging three per game themselves.
Munster have retained possession at 97% of rucks and mauls, a tournament high.
In team news ahead of the game, number eight Ernst Joubert will make his 100th appearance for Saracens after being named to start.
In other news, Saracens welcome back the England quintet of Brad Barritt, Chris Ashton, Alex Goode, Owen Farrell and Mako Vunipola into the matchday 23. Barritt, Ashton, Goode and Farrell start the match while Vunipola is named on the bench.
Kelly Brown and Schalk Brits also return to the side after being rested last weekend.
Adam Powell, Jackson Wray, Jacques Burger, Justin Melck, Alistair Hargreaves and Joe Maddock all miss out through injury.
Meanwhile, Munster have made seven changes to the side that faced Edinburgh, with two of those positional. James Coughlan, Ronan O'Gara and Keith Earls missed out last time through injury and Felix Jones came on as a replacement in that game on his comeback.
Earls returned to the outside centre berth last week after the November internationals and he retains that jersey at the expense of Casey Laulala who offers a very potent back option.
And with back-rowers Niall Ronan, Sean Dougall, and Tommy O'Donnell all on the injured list, opportunity knocks for Dave O'Callaghan who has been handed the number six shirt.
Munster: 15 Felix Jones, 14 Doug Howlett (capt), 13 Keith Earls, 12 James Downey, 11 Simon Zebo, 10 Ronan O'Gara, 9 Conor Murray, 8 James Coughlan, 7 Peter O'Mahony, 6 Dave O'Callaghan, 5 Donnacha Ryan, 4 Donncha O'Callaghan, 3 BJ Botha, 2 Mike Sherry, 1 David Kilcoyne.Replacements: 16 Damien Varley, 17 Wian du Preez, 18 Stephen Archer, 19 Billy Holland, 20 Peter Butler, 21 Duncan Williams, 22 Ian Keatley, 23 Casey Laulala.
Saracens: 15 Alex Goode, 14 Chris Ashton, 13 Owen Farrell, 12 Brad Barritt, 11 David Strettle, 10 Charlie Hodgson, 9 Neil de Kock, 8 Ernst Joubert, 7 Will Fraser, 6 Kelly Brown, 5 Mouritz Botha, 4 Steve Borthwick, 3 Matt Stevens, 2 Schalk Brits, 1 Rhys Gill.Replacements: 16 John Smit, 17 Mako Vunipola, 18 Petrus du Plessis, 19 George Kruis, 20 Andy Saull, 21 Richard Wigglesworth, 22 Joel Tomkins, 23 Chris Wyles.
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The entire All Blacks apparel line has been updated for 2013/14. Check out the New Zealand All Blacks polo.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Gilbert Blitz 8S rugby cleat is a great cleat at a great price of $69.99. Get a new pair of cleats today.
A cool looking all black rugby cleat with the high performance adidas is known for. Get in the Gear!
Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
The All Blacks Performance t-shirt is black with hints of blue from the training jersey. Very Cool.
The New Zealand All Blacks training jersey for 2013/14. Get in the Gear!
The USA Rugby Pro Alternate rugby jersey is perfect for any fan of the Eagles. Get yours to wear during the summer Test matches.
The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.