Harlequins have recalled a number of first-choice players for their Aviva Premiership clash at home to Wasps on Saturday night (kick-off 8pm).
Joe Gray, George Robson, Ugo Monye, George Lowe, Jordan Turner-Hall and Rob Buchanan all return to the side at the Twickenham Stoop following international duty with the England Saxons
After missing the recent LV= Cup double-header, winger Tom Williams, fly-half Nick Evans and captain Nick Easter all return for the league clash.
The defending champions currently sit two points clear at the top of the table and are on a 12-match winning streak in all competitions going back to November.
Wasps have named Billy Vunipola in the starting line-up at No 8 after he was released back from the England squad.
The visitors have also made a host of changes following their LV= Cup defeat to Sale, with their ranks boosted by England Saxons returnees.
Joe Simpson and Nick Robinson are named in the halves, while the back-three of Tom Varndell, Christian Wade and skipper Hugo Southwell is re-united.
Wasps director of rugby Dai Young said: "There has been a good atmosphere around the place this week in leading up to the first Aviva Premiership game in over a month.
"Harlequins are a side who tend to negotiate the international periods very well so we know how tough a task we will have on Saturday night.
"They showed us how quickly they can change a game on the opening day of the season and we will have to be at our best to get a result this weekend."
Harlequins: 15 Ross Chisholm, 14 Tom Williams, 13 George Lowe, 12 Matt Hopper, 11 Ugo Monye, 10 Nick Evans, 9 Karl Dickson, 8 Nick Easter (c), 7 Luke Wallace, 6 Tom Guest, 5 George Robson, 4 Charlie Matthews, 3 James Johnston, 2 Joe Gray, 1 Mark Lambert.
Replacements: 16 Rob Buchanan, 17 Darryl Marfo, 18 Will Collier, 19 Sam Twomey, 20 Maurie Fa'asavalu, 21 Ollie Lindsay-Hague, 22 Rory Clegg, 23 Jordan Turner-Hall.
Wasps: 15 Hugo Southwell (c), 14 Christian Wade, 13 Elliot Daly, 12 Chris Bell, 11 Tom Varndell, 10 Nick Robinson, 9 Joe Simpson, 8 Billy Vunipola, 7 Sam Jones, 6 Ashley Johnson, 5 Marco Wentzel, 4 James Cannon, 3 Phil Swainston, 2 T Rhys Thomas, 1 Zak Taulafo.
Replacements: 16 Tom Lindsay, 17 Tim Payne, 18 Will Taylor, 19 Alex Rae, 20 Tinus Du Plessis, 21 Charlie Davies, 22 Stephen Jones, 23 Charlie Hayter.
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