Horacio Agulla is poised to make his Bath debut in the west country derby.
Agulla joined Bath from Leicester in the summer but has had to wait to make his first appearance due to his international commitments with Argentina.
The winger is named on the bench for the clash, with Stuart Hooper also returning to the squad.
The only change to the starting XV comes in the back row, with Carl Fearns coming in for the benched Will Skuse.
Australia international Dean Mumm returns to the Chiefs line-up.
Mumm missed the Heineken Cup defeat to Clermont last time out due to personal reasons, however he will replace Tom Hayes in the second row.
Gonzalo Camacho also comes into the starting XV, with the Argentina international replacing the benched Ian Whitten.
Scrum-half Kevin Barrett and academy graduate Dave Ewers are also included among the replacements.
Bath: 15 Nick Abendanon, 14 Kyle Eastmond, 13 Dan Hipkiss, 12 Ben Williams, 11 Tom Biggs, 10 Stephen Donald, 9 Michael Claassens, 8 Ben Skirving, 7 Francois Louw (c), 6 Carl Fearns, 5 Dave Attwood, 4 Dominic Day, 3 David Wilson, 2 Lee Mears, 1 Paul James.
Replacements: 16 Brett Sharman, 17 Nathan Catt, 18 Anthony Perenise, 19 Stuart Hooper, 20 Will Skuse, 21 Mark McMillan, 22 Sam Vesty, 23 Horacio Agulla.
Exeter: 15 Luke Arscott, 14 Gonzalo Camacho, 13 Phil Dollman, 12 Jason Shoemark, 11 Matt Jess, 10 Gareth Steenson, 9 Haydn Thomas, 8 Richard Baxter, 7 James Scaysbrook, 6 Tom Johnson, 5 James Hanks, 4 Dean Mumm, 3 Carl Rimmer, 2 Simon Alcott, 1 Brett Sturgess.
Replacements: 16 Chris Whitehead, 17 Ben Moon, 18 Chris Budgen, 19 Aly Muldowney, 20 Dave Ewers, 21 Kevin Barrett, 22 Ignacio Mieres, 23 Ian Whitten.
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