Lewis Moody, Francois Louw, Lee Mears and David Wilson are all named in the 23. After an impressive debut appearance last week in the win over the Dragons, Anthony Perenise makes his first start for the club, replacing Mark Lilley in the front row.
South African flanker Louw makes his first appearance in a pack whilst Mears, Wilson and Moody are named on the bench, along with captain Stuart Hooper who returns from injury.
Worcester make two changes to the team which beat Wasps last week.
Lock Ben Gulliver will start his first game for the Warriors having arrived at the club from Cornish Pirates in the summer.
Hooker Ollie Hayes is also named in the starting line-up for his first start and youngsters Will Radburn and Nile Dacres are named among the replacements.
Bath: Cuthbert, Woodburn, Hipkiss, Banahan, Abendanon, Heathcote, Cook, Catt, Batty, Perenise, Spencer, Caldwell, Beattie, Louw, Skirving, Reps: Mears, Beech, Wilson, Hooper, Moody, Keyte, Vesty, Biggs
Worcester: Arscott, Short, Pennell (c), Crockett, Drauniniu, Carlisle, Frost, Porter, Hayes, Tomaszczyk, Jones, Gulliver, Betty, Kvesic, Balding Reps: Douglas, Radburn, Currie, Dacres, Muagututia, Gray, Tu'ipulotu, Penn
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