Royce Cadman and Luke Williams will make their debuts for the hosts in a side captained by scrum-half Joe Bedford.
"There are quite a few new faces on the teamsheet," said Dragons head coach Darren Edwards. "Several of our development and academy players will be out on the park as well as representatives from our Premiership sides."
Bath will also turn to youth for the clash - handing first starts to prop Charlie Beech, lock Will Spencer and wing Olly Woodburn.
Academy hooker Will Tanner and Samoan prop Anthony Perenise are also hoping to take their bows from the replacements' bench.
Fly-half Tom Heathcote partners Mark McMillan in the half-backs, and Matt Banahan goes straight back into the side at centre having returned from the World Cup.
Dragons: M Thomas, Chavhanga, Riley, Robling, Pewtner, M Jones, Bedford (c); N Williams, Buckley, Buck, Cadman, Morgan, Groves, Waters, Ellis.
Replacements: Parry, Gustafson, Jenkins, Sidoli, Brown, Evans, Williams, Jones.
Bath: Cuthbert, Woodburn, Carraro, Banahan, Biggs, Heathcote, McMillan; Beech, Batty, Lilley, Spencer, Attwood, Beattie (c), Mercer, Taylor.
Replacements: Tanner, Catt, Perenise, Caldwell, Skuse, Cook, Roberts, Abendanon.
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The Barbarians are one of the top invitational rugby sides with a long history and classic rugby jersey.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Lions get ready for their matches with this green training jersey. It's what the players wear. Get in the Gear!
A cool looking all black rugby cleat with the high performance adidas is known for. Get in the Gear!
Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
$29.99
The Lions are ready to get their Australia tour underway. They arrive in Perth on Monday.
The New Zealand All Blacks training jersey for 2013/14. Get in the Gear!
The USA Rugby Pro Alternate rugby jersey is perfect for any fan of the Eagles. Get yours to wear during the summer Test matches.
The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.