Ireland wing Simon Zebo will miss the remainder of the Six Nations after breaking a bone in his foot in the 12-6 defeat to England.
Zebo will undergo an operation on Monday to repair the damage incurred in the 10th minute of a brutal Test in Dublin and has been ruled out for up to 10 weeks.
The prognosis on Jonathan Sexton's hamstring injury was less grave with coach Declan Kidney estimating a two-week lay-off for the Leinster fly-half, who was replaced by Ronan O'Gara after half an hour.
Flanker Sean O'Brien (tight hamstring), lock Mike McCarthy (knee ligament strain), centre Brian O'Driscoll (twisted ankle) and lock Donnacha Ryan (back) also sustained injuries, but have yet to be ruled out against Scotland in two weeks time.
"Simon will have surgery tomorrow. Jonny will have a scan either later tonight or tomorrow," Kidney said.
"It looks like a couple of weeks for Jonny, but it would be wrong to try and second guess the outcome. We'll know more by Tuesday.
"It's been an attritional couple of games and we had a few injuries leading into the tournament, but that's the way it goes."
Gilbert has released a new line of rugby cleats. The Gilbert Virtuo 8S is part of the exciting new product. Check it out.
The Barbarians are one of the top invitational rugby sides with a long history and classic rugby jersey.
The Nike Tiempo is a solid rugby cleat and one of few styles still made from full-grain natural leather.
The Lions get ready for their matches with this green training jersey. It's what the players wear. Get in the Gear!
A cool looking all black rugby cleat with the high performance adidas is known for. Get in the Gear!
Wear the crest of the British and Irish Lions on your t-shirt. A great look for the summer.
$29.99
The Lions are ready to get their Australia tour underway. They arrive in Perth on Monday.
The New Zealand All Blacks training jersey for 2013/14. Get in the Gear!
The USA Rugby Pro Alternate rugby jersey is perfect for any fan of the Eagles. Get yours to wear during the summer Test matches.
The NEW All Blacks 2013/14 jersey has arrived at World Rugby Shop. Dare to wear the colors of the All Blacks.