The Chiefs will be assessing their backline resources in their build-up the start of their Super Rugby title defence.
Midfielders Andrew Horrell, Richard Kahui, and Charlie Ngatai are all sidelined, along with fullback Robbie Robinson.
Inside centre Bundee Aki also took a knock to his shoulder, in their final pre-season outing - a 25-21 win over the Hurricanes in Mangatainoka at the weekend.
The Chiefs dominated for the majority of the first half taking a 10-0 lead into the break thanks to tries to scrumhalf Tawera Kerr-Barlow from a quick tap and wing Asaeli Tikoirotuma, who crossed the chalk after a pass from Hika Elliot.
After the half-time whistle, Bundee Aki dotted down to give the Chiefs a 17-0 lead which Hurricane wing Julian Savea replied to.
Playing at centre for the Chiefs, Tim Nanai-Williams scored to give the visitors a 15-point lead.
The Hurricanes lifted their game after some substitutions, with Ardie Savea adding the spark. Savea and Faifili Levave both scored making it 22-21.
A late penalty to Gareth Anscombe sealed the match for the defending Super Rugby Champions.
Chiefs coach Dave Rennie said he was "happy" with the hit out.
"We knew it would be a tough game, the Hurricanes have been racking up a lot of points - they are stronger on paper than last year," Rennie said.
"Our boys who jumped in at foreign positions like Tim and Gareth did well.
"It was pretty combative at the breakdown which meant a few penalties and we've have got a few things to work on.
"Now with a short turn around we will be focusing on review and recovery."